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J Physiol Vol 183, Issue 1 pp 152-166
Copyright © 1966 by The Physiological Society
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Potentiometric measurement of membrane action potentials in frog muscle fibres

 B. Frankenhaeuser, B. D. Lindley and R. S. Smith

1. A potentiometric method for recording membrane action potentials from small segments of isolated skeletal muscle fibres has been described.

2. The value of the method in muscle physiology has been appraised by recording from fast and slow skeletal muscle fibres of the frog under a variety of conditions.

3. Artifacts associated with this method have been described and their sources investigated.






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