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J Physiol Vol 184, Issue 3 pp 663-672
Copyright © 1966 by The Physiological Society
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The subcellular localization of kallikrein, amylase and acetylcholine in the submaxillary gland of the guinea-pig

K. D. Bhoola and C. W. Ogle

1. The subcellular distribution pattern of kallikrein was compared with that of amylase and acetylcholine in submaxillary gland homogenates of the guinea-pig.

2. Kallikrein was located in particles which sedimented in the nuclear (46%) and mitochondrial (17%) fractions. These particles were probably similar if not identical to zymogen granules.

3. The above observations would support a digestive role for salivary kallikrein.







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