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J Physiol Vol 184, Issue 4 pp 964-969
Copyright © 1966 by The Physiological Society
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Experiments on the genesis of bubbles as a result of rapid decompression

M. J. Lever, K. W. Miller, W. D. M. Paton and E. B. Smith

1. The time course of intravascular bubble formation in mice after rapid decompression from 150 Lb/sq. in. has been followed in vivo in a flap preparation of thoracic and abdominal skin.

2. Gas appeared first in the arteries, moving distally after a latent period of 3 min or more. Then bubbles appeared, moving centrally, in the venous system.

3. The arterial bubbles could not be attributed to air forced into the circulation from the lungs or lumen of the gut.







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