HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Dainty, J. Articles by House, C. R. Search for Related Content PubMed PubMed Citation Articles by Dainty, J. Articles by House, C. R.

1. Measurements of the diffusional permeability, P_d, of tritiated water in isolated frog skin bathed in sulphate Ringer have been made under different stirring conditions.

2. The mean ± S.E. values for P_d were found to be (6·5 ± 0·3), (7·9 ± 0·5), (9·7 ± 0·7) and (11·1 ± 0·8) x 10^-5 cm sec^-1 at 120, 300, 500 and 1000 rev/min. It is considered that these results indicate the existence of `unstirred layers' associated with frog skin.

3. The hydraulic conductivity, L_p, of the skin in sulphate Ringer was found to be (2·36 ± 0·07) x 10^-7 cm sec^-1 atm^-1 (± S.E. of estimate), and no marked increase in this value for L_p was found when the stirring rate was increased from 0 to 500 rev/min.

4. It is considered that these results show that previous comparisons of the relative magnitudes of L_pRT/_w (where _w is the partial molar volume of water) and P_d for frog skin have been in error because of the presence of `unstirred layers'.

5. The bearing of our results and other evidence on the question of pores in cell membranes has been discussed.