HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Campbell, H. J. Articles by Gallardo, E. Search for Related Content PubMed PubMed Citation Articles by Campbell, H. J. Articles by Gallardo, E.

1. Intrapituitary infusions of extracts made from the median eminence of various species at different ages were found to excite secretion of gonadotrophic hormone as shown by consequent ovulation, presumably due to their content of luteinizing hormone-releasing factor (LRF).

2. Extracts from very immature animals (e.g. new-born rabbits and rats; 1-2-month-old calves) were found to be highly active with regard to LRF content.

3. Extracts from foetal rabbits at 20 days of gestation showed no evidence of containing LRF.

4. It is suggested that (a) LRF may have a trophic action upon the anterior pituitary gland during the pre-puberal phase of life, and that (b) the first formation of LRF coincides with the development of the primary plexus of the pituitary portal system.