HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Brick, I. Articles by Roddie, I. C. Search for Related Content PubMed PubMed Citation Articles by Brick, I. Articles by Roddie, I. C.

1. Blood flow was simultaneously measured by venous-occlusion plethysmography in both forearms of ten healthy men.

2. Voluntary overbreathing to produce about 8 times the resting ventilation caused a vasodilatation similar in both forearms.

3. When one forearm was treated with an intra-arterial infusion of propranolol, a beta adrenergic blocking agent, the vàsodilator response was reduced by an average of 28%, the reduction was significant (P < 0·01).

4. The failure of propranolol to abolish the vasodilator response was not due to incomplete block of beta adrenergic receptors since the dose of propranolol used reversed the vasodilator response to an intravenous infusion of adrenaline.

5. The results suggest that the vasodilator response to voluntary hyperventilation can be explained partly, but not entirely, by the release into the circulation of an adrenaline-like substance.