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1. The ability of two human subjects to produce sweat was measured before and after immersion for up to 4 hr in water at 32-36° C (soak).

2. The ability to produce sweat declined about 4 times as rapidly when the subject was soaked at 36° C as at 32° C.

3. The rate of decline characteristic of soaking at 36° C was shown by subjects exercising in water at 35° C, but not at rest at 35° C. The difference appeared to be related to the presence or absence of moderate sweating (300 g/hr) during the soak. At higher rates there was no further increase in the rate of decline.

4. Soaking at 39° C for 5 min, after which the water temperature was reduced to 33° C, caused a decline consistent with the supposition that while the subject was sweating the rate of decline was the same as that at 36° C and for the rest of the time the same as that at 32° C.

5. It is concluded that the rate of decline is increased if the sweat ducts are perfused, and some possible mechanisms are discussed.