| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1. Post-tetanic potentiation (PTP) was studied at the neuromuscular junction of the frog. The magnitude and time course of PTP was dependent on the number of stimuli in the tetanus, rather than on the frequency or duration of the tetanus. At low temperature the maximum amplitude of PTP was unchanged, but the time course was prolonged.
2. The magnitude and time course of PTP was accounted for quantitatively by estimated changes in the fraction of transmitter released per stimulus.
3. As external [Ca] was reduced, the time for decay of PTP was decreased. The maximum amplitude of PTP, measured with respect to control amplitude at the same [Ca], was unchanged, but occurred at earlier times. The time course of PTP was dependent only on the [Ca] present during the tetanus.
4. It is concluded that PTP is associated with an intracellular accumulation of Ca during the tetanus.
This article has been cited by other articles:
|
|
 |
|
  E. Garcia-Perez, D. C. Lo, and J. F. Wesseling Kinetic Isolation of a Slowly Recovering Component of Short-Term Depression During Exhaustive Use at Excitatory Hippocampal Synapses J Neurophysiol, August 1, 2008; 100(2): 781 - 795. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. L. P. Habets and J. G. G. Borst Dynamics of the readily releasable pool during post-tetanic potentiation in the rat calyx of Held synapse J. Physiol., June 1, 2007; 581(2): 467 - 478. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Felmy and H. von Gersdorff Late Switch for Post-Tetanic Potentiation: Once Again It's Ca2+. Focus on "An Increase in Calcium Influx Contributes to Post-Tetanic Potentiation at the Rat Calyx of Held Synapse" J Neurophysiol, December 1, 2006; 96(6): 2840 - 2841. [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Kalkstein and K. L. Magleby Augmentation Increases Vesicular Release Probability in the Presence of Masking Depression at the Frog Neuromuscular Junction J. Neurosci., December 15, 2004; 24(50): 11391 - 11403. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. F. Gainey Jr and M. J. Greenberg Nitric oxide mediates seasonal muscle potentiation in clam gills J. Exp. Biol., October 1, 2003; 206(19): 3507 - 3520. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Niven and M. Burrows Spike Width Reduction Modifies the Dynamics of Short-Term Depression at a Central Synapse in the Locust J. Neurosci., August 20, 2003; 23(20): 7461 - 7469. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Jin and R. D. Hawkins Presynaptic and Postsynaptic Mechanisms of a Novel Form of Homosynaptic Potentiation at Aplysia Sensory-Motor Neuron Synapses J. Neurosci., August 13, 2003; 23(19): 7288 - 7297. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
