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1. During the initial stages of progressive hypoxia in ducks and pigeons (P_{a, O2} 100 60 mm Hg) there were no significant changes in heart rate, blood pressure or oxygen uptake, but respiratory frequency increased.

2. As hypoxia became more profound (P_{a, O2} 60 30 mm Hg), there was a significant tachycardia, and blood pressure fell slightly in both animals. Respiratory frequency continued to increase in both species, and ducks were able to maintain their oxygen uptake at control levels at a lower P_{a, O2} than pigeons.

3. The response to progressive hypoxia of pigeons and ducks was compared with that of the domestic fowl. The former two birds could maintain control of their cardiovascular system at a lower environmental oxygen concentration than the latter. Arterial P_O2 followed a similar course in all three birds in relation to environmental oxygen content. Pigeons and ducks were therefore able to endure a lower arterial P_O2 than chickens.