HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Cohen, L. B. Articles by Keynes, R. D. Search for Related Content PubMed PubMed Citation Articles by Cohen, L. B. Articles by Keynes, R. D.

1. Changes in light scattering from stimulated crab leg nerves were measured in an effort to study changes in structure that occur during the action potential.

2. The peak changes in scattering after individual stimuli were 10^-4-10^-5 of the resting scattering; signal averaging techniques were used to increase the signal-to-noise ratio.

3. During the compound action potential there was a transient increase in the 90° scattering which reached a peak about 20 msec after the stimulus. This increase was probably not due to a change in axon volume. Its time course was somewhat slower than that of birefringence changes measured at the same time.

4. In normal sea water the transient increase was followed by a longer lasting (persistent) decrease in scattering. This persistent decrease could be converted to an increase by reducing the tonicity of the sea water or by raising the external refractive index. This scattering change may represent a swelling of the axon resulting from the ionic exchanges that occur during the action potential.

This article has been cited by other articles:

				M. Fukuda, U. M. Rajagopalan, R. Homma, M. Matsumoto, M. Nishizaki, and M. Tanifuji Localization of Activity-dependent Changes in Blood Volume to Submillimeter-scale Functional Domains in Cat Visual Cortex Cereb Cortex, June 1, 2005; 15(6): 823 - 833. [Abstract] [Full Text] [PDF]

				X.-C. Yao, A. Foust, D. M. Rector, B. Barrowes, and J. S. George Cross-Polarized Reflected Light Measurement of Fast Optical Responses Associated with Neural Activation Biophys. J., June 1, 2005; 88(6): 4170 - 4177. [Abstract] [Full Text] [PDF]

				Y. Momose-Sato, K. Sato, A. Hirota, and K. Kamino GABA-Induced Intrinsic Light-Scattering Changes Associated With Voltage-Sensitive Dye Signals in Embryonic Brain Stem Slices: Coupling of Depolarization and Cell Shrinkage J Neurophysiol, April 1, 1998; 79(4): 2208 - 2217. [Abstract] [Full Text] [PDF]

				D. M. Rector, G. R. Poe, M. P. Kristensen, and R. M. Harper Light Scattering Changes Follow Evoked Potentials From Hippocampal Schaeffer Collateral Stimulation J Neurophysiol, September 1, 1997; 78(3): 1707 - 1713. [Abstract] [Full Text] [PDF]