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1. Measurements of the instantaneous K current, under voltage clamp, were obtained using paired de- and hyperpolarizing clamp pulse sequences. The instantaneous potassium currentvoltage relations so obtained showed constant field type rectification.
2. The zero current potential of the instantaneous K currentvoltage relation, when examined as a function of the K concentration, [K]o, behaved like a Nernst concentration cell potential for K. It was concluded that during the generation of the delayed current, the membrane shows substantial selectivity for K.
3. The equivalent of the `FrankenhaeuserHodgkin space' in Myxicola was found to be more difficult to load with K ions than in squid. The thickness of the space may be taken as effectively about seven times larger than in squid.
4. Myxicola axons were found to show little or no long time constant delayed current inactivation as has been described for squid.
5. In high [K]o a negative steady-state conductance was observed which was predictable from the independence principle with a suitable scaling factor.
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J. R. Clay Excitability of the Squid Giant Axon Revisited J Neurophysiol, August 1, 1998; 80(2): 903 - 913. [Abstract] [Full Text] [PDF] |
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