HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Afonso, S. Articles by Rowe, G. G. Search for Related Content PubMed PubMed Citation Articles by Afonso, S. Articles by Rowe, G. G.

1. In previous studies adenosine has been postulated to be the mediator in coronary blood flow regulation and aminophylline was found to inhibit the coronary vasodilator action of adenosine. The present study was performed to determine whether aminophylline inhibits coronary vasodilatation induced by hypoxia.

2. Coronary and systemic haemodynamic and metabolic effects of hypoxia were studied in anaesthetized dogs before and after aminophylline. Aminophylline did not influence coronary vasodilatation induced by hypoxia.

3. These results are held not to lend support to the hypothesis that adenosine is the metabolite responsible for the regulation of coronary blood flow.

This article has been cited by other articles:

				D. J. Cheek, J. M. McHugh, J. Blood-Siegfried, J. F. McFetridge, and B. S. Turner A Historical Perspective on the Discovery of Adenyl Purines Biol Res Nurs, April 1, 2000; 1(4): 265 - 275. [Abstract] [PDF]