HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Allen, G. I. Articles by Toyama, K. Search for Related Content PubMed PubMed Citation Articles by Allen, G. I. Articles by Toyama, K.

1. The cerebellar integration of sensory inputs to Deiters neurones was investigated in decerebrate cats. In some preparations decerebration was combined with transection of the olivocerebellar fibres.

2. In the latter preparations peripheral nerve impulses generally produced a response consisting of a sequence of the following post-synaptic potentials: (i) an initial e.p.s.p. (d₁), (ii) early i.p.s.p. (h₁), (iii) later i.p.s.p. (h₂).

3. The mean latencies of d₁, h₁ and h₂ were 5·7, 7·3 and 9·8 msec from the forelimb nerves, and 7·5, 9·0 and 13·4 msec from the hind limb nerves, respectively.

4. The stimulus intensity—response relation indicates that the Group I muscle afferents as well as the low threshold cutaneous afferents contribute to the response.

5. In the preparations with the intact inferior olive there were additional components of the post-synaptic potentials: a later e.p.s.p. (d₂) and another later i.p.s.p. (h₃), their mean latencies being 15·3 and 19·7 msec from the forelimb nerves, and 18·0 and 21·3 msec from the hind limb nerves, respectively.

6. The d₁ and h₂ components were attributed to the mossy fibre afferents and d₂ and h₃ to the climbing fibres; d₁ and d₂ were due to excitation through the collaterals of the mossy and climbing fibres, and h₂ and h₃ to inhibition from Purkyn cells activated by the mossy and climbing fibres, respectively. h₁ was too early to be produced through the cerebellum, and was probably mediated by inhibitory neurones in the reticular formation.