HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hori, T. Articles by Nakayama, T. Search for Related Content PubMed PubMed Citation Articles by Hori, T. Articles by Nakayama, T.

1. Single unit activities were recorded with five-barrelled micropipettes from the thermo-responsive neurones in the preoptic area and the mid-brain reticular formation in urethanized rabbits. 5-hydroxytryptamine (5-HT), noradrenaline (NA) and acetylcholine (ACh) were applied micro-iontophoretically to the immediate vicinity of the recording cells.

2. Out of seventeen warm-responsive neurones recorded in the preoptic area, fifteen neurones responded to 5-HT with the increase in firing rate and two showed no response. Thirteen out of seventeen warm-units decreased their firing rate in response to application of NA and four were not affected. ACh had no effect on any of the warm-units examined.

3. Six out of seven cold-units in the preoptic area were depressed by 5-HT, while NA excited five of six units studied. None of the cold-units were influenced by ACh.

4. These results are in good agreement with the changes in rectal temperature produced by 5-HT and NA micro-injected into the hypothalamus in rabbits.

5. In the mid-brain reticular formation, 5-HT excited all of fourteen cold-responsive neurones. Of these, eight cold-units were depressed and six were unaffected by NA, while ACh excited six units and had no effect on eight units. All of the five warm-responsive units were inhibited by 5-HT and none were influenced by NA. Thus, the responses of reticular thermoresponsive neurones to 5-HT and NA were opposite to those of the preoptic thermo-responsive neurones.

This article has been cited by other articles:

				G. Yoshimichi, H. Yoshimatsu, T. Masaki, and T. Sakata Orexin-A Regulates Body Temperature in Coordination with Arousal Status Experimental Biology and Medicine, May 1, 2001; 226(5): 468 - 476. [Abstract] [Full Text]

				T. Oka, K. Oka, and T. Hori Mechanisms and Mediators of Psychological Stress-Induced Rise in Core Temperature Psychosom Med, May 1, 2001; 63(3): 476 - 486. [Abstract] [Full Text] [PDF]