HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Blair, J. A. Articles by Matty, A. J. Search for Related Content PubMed PubMed Citation Articles by Blair, J. A. Articles by Matty, A. J.

1. Everted rings of rat intestine were used to study the initial uptake rate of folic acid at various concentrations and incubation temperatures in vitro.

2. Folic acid was accumulated linearly for periods of at least 30 min.

3. The initial uptake rate was found to reach a constant value as the concentration of folic acid in the incubation medium was increased above 5 x 10^-6 M.

4. Reducing the temperature of incubation from 37 to 27° C gave small Q₁₀ values at either end of the concentration range.

5. Transfer of folic acid into the serosal compartment of everted sacs was shown to undergo a rate reduction in the same concentration range.

6. A mechanism for folic acid transport is suggested in which folic acid is converted to the neutral species at the mucosal surface in an acid microclimate.