HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kidokoro, Y Search for Related Content PubMed PubMed Citation Articles by Kidokoro, Y

1. The developmental changes of the cell membrane electrical properties were studied with micro-electrodes in a rat skeletal muscle cell line. 2. The resting potentials in myoblasts were minus 71 plus or minus 3 mV (mean plus or minus S.D.) and those in myotubes which were formed by fusion of myoblasts were minus 69 plus or minus 3 mV. There was no developmental change in the resting potential during the period examined. 3. The ionic mechanism for the resting potential was the same in myoblasts and myotubes. The resting membrane was almost exclusively permeable to K ions, while permeability to Na ions was not detectable. There was a small permeability to Cl ions. 4. The specific membrane resistance and capacitance were 8 k omega. cm-2 and 1 muF/cm-2 for myoblasts and 12 k omege. cm-2 and 5 muF/cm-2 for myotubes, respectively. 5. Action potentials in myoblasts were evoked by anode break stimulation. They were small and did not overshoot zero membrane potential. The action potentials in myotubes were larger, and had an average overshoot of 32 plus or minus 7 mV and a maximum rate of rise of 93 plus or minus 28 V/sec. 6. The current-voltage relation was examined. Delayed rectification was found in myotubes but not in myoblasts.

This article has been cited by other articles:

				A. Shtifman, C. Paolini, J. R. Lopez, P. D. Allen, and F. Protasi Ca2+ influx through {alpha}1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle Am J Physiol Cell Physiol, January 1, 2004; 286(1): C73 - C78. [Abstract] [Full Text] [PDF]

				P. Elsner, B. Quistorff, T. S. Hermann, J. Dich, and N. Grunnet Regulation of glycogen accumulation in L6 myotubes cultured under optimized differentiation conditions Am J Physiol Endocrinol Metab, December 1, 1998; 275(6): E925 - E933. [Abstract] [Full Text] [PDF]

				Y. Kidokoro, S. Heinemann, D. Schubert, B. L. Brandt, and F. G. Klier Synapse Formation and Neurotrophic Effects on Muscle Cell Lines Cold Spring Harb Symp Quant Biol, January 1, 1976; 40(0): 373 - 388. [Abstract] [PDF]

				M. J. Dennis and C. A. Ort Physiological Properties of Nerve-Muscle Junctions Developing In Vivo Cold Spring Harb Symp Quant Biol, January 1, 1976; 40(0): 435 - 442. [Abstract] [PDF]