HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Daw, N W Articles by Wyatt, H J Search for Related Content PubMed PubMed Citation Articles by Daw, N W Articles by Wyatt, H J

1. Kittens were reared in the dark from birth except for a period each day when they were put inside a stationary transparent cylinder, around which a drum with vertical black and white stripes on the inside, rotated in one direction. After the end of the period of exposure, we recorded a sample of single cells from their visual cortices, and analysed each cell for direction and orientation sensitivity and other properties. 2. Two kittens were placed inside the drum, rotating rightward, for 2 hr each seekday from 3 1/2 to 7 weeks of age. A greater proportion of the directionally sensitive cells in their cortices showed a preference for rightward movement. 3. Six other kittens were placed inside the drug for 1 hr each weekday from 2 to 12 weeks of age with the drum rotating leftward up to a particular changeover age, then rightward until 12 weeks. The changeover point occurred at 21, 26, 28, 33, 35 and 51 days for different kittens. A changeover earlier than 4 weeks of age led to a preponderance of cells preferring rightward movement. A changeover later than 5 weeks of age led to a preponderance of cells preferring leftward movement. Comparison of these results with others on monocular deprivation suggests that the peak of the critical period for directional deprivation may occur earlier than the peak of the critical period for monocular deprivation. 4. None of the samples of cells showed a preponderance of cells specific for vertical orientations. It is unclear whether this negative effect resulted from the presence of some horizontal contours during exposure, or some more fundamental cause.

This article has been cited by other articles:

				B. M. Hooks and C. Chen Vision Triggers an Experience-Dependent Sensitive Period at the Retinogeniculate Synapse J. Neurosci., April 30, 2008; 28(18): 4807 - 4817. [Abstract] [Full Text] [PDF]

				D. S. Liao, T. E. Krahe, G. T. Prusky, A. E. Medina, and A. S. Ramoa Recovery of Cortical Binocularity and Orientation Selectivity After the Critical Period for Ocular Dominance Plasticity J Neurophysiol, October 1, 2004; 92(4): 2113 - 2121. [Abstract] [Full Text] [PDF]

				C. J. Beaver, Q. S. Fischer, Q. Ji, and N. W. Daw Orientation Selectivity Is Reduced by Monocular Deprivation in Combination With PKA Inhibitors J Neurophysiol, October 1, 2002; 88(4): 1933 - 1940. [Abstract] [Full Text] [PDF]

				N. W. Daw, B. Gordon, K. D. Fox, H. J. Flavin, J. D. Kirsch, C. J. Beaver, Q.-H. Ji, S.N.M. Reid, and D. Czepita Injection of MK-801 Affects Ocular Dominance Shifts More Than Visual Activity J Neurophysiol, January 1, 1999; 81(1): 204 - 215. [Abstract] [Full Text] [PDF]

				N. W. Daw Critical Periods and Amblyopia Arch Ophthalmol, April 1, 1998; 116(4): 502 - 505. [Abstract] [Full Text] [PDF]