HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Quin, J W Articles by Shannon, A D Search for Related Content PubMed PubMed Citation Articles by Quin, J W Articles by Shannon, A D

1. Experiments have been performed in sheep to determine the contribution of lymph formed within a lymph node to the total protein output in lymph leaving the node. 2. The lymphatic duct leaving the popliteal lymph node was cannulated and the protein and lymphocyte output in efferent lymph determined. The afferent lymph flow to the popliteal node was then diverted and lymph formed only within the lymph node collected from the efferent cannula. It appeared from the results that the popliteal lymph node forms lymph at the rate of approximately 1 ml. per hour and may contribute 30-50% of the protein output observed in efferent lymph. 3. The importance of lymph formation within the lymph node varied between nodes found in different regions of the body. This was due in part to the different protein concentrations in the afferent lymph to the different nodes. 4. A positive correlation was found between the protein and lymphocyte concentrations in efferent lymph from the popliteal lymph node in seven out of eleven sheep and in lymph formed within the popliteal lymph node in two out of three sheep. It is suggested that this relationship may be due to an increased transfer of plasma proteins through the post-capillary venules in the lymph node accompanying the continual traffic of lymphocytes across the wall of these vessels. The results indicated that the protein transfer across the post-capillary venules was not an indiscriminate transfer of plasma per se but a selective transport from the blood plasma compartment based on molecular size.

This article has been cited by other articles:

				N. Ono, R. Mizuno, and T. Ohhashi Effective permeability of hydrophilic substances through walls of lymph vessels: roles of endothelial barrier Am J Physiol Heart Circ Physiol, October 1, 2005; 289(4): H1676 - H1682. [Abstract] [Full Text] [PDF]

				C. He, A. J. Young, C. A. West, M. Su, M. A. Konerding, and S. J. Mentzer Stimulation of regional lymphatic and blood flow by epicutaneous oxazolone J Appl Physiol, September 1, 2002; 93(3): 966 - 973. [Abstract] [Full Text] [PDF]