HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Gardner, D Search for Related Content PubMed PubMed Citation Articles by Gardner, D

1. In cholinergic neurones BL4, BL5, BR4, and BR5 of Aplysia buccal ganglia, each action potential is followed, in the same cell, by a curare- and high-Mg-sensitive hyperpolarizing after-potential which is enhanced by Ca. 2. In voltage-clamped neurons, substracting currents recorded in curare from currents recorded in sea water reveals that this potential is due to curare-sensitive currents which rise to a peak, then decay exponentially with an apparently voltage-independent time constant of 43 msec. Currents are produced by a voltage-independent, Ca-enhanced, conductance change with a 0-26 mumho peak and a -64 mV reversal potential. The curare-sensitive conductance is also sensitive to high Mg. 3. Both after-potential and curare- or Mg-sensitive current follow each action potential without failures, even in threshold-raising 80 mM-Ca-144-mM-Mg solutions. 4. Both after-potential and current decrease with repetitive firing or short inter-spike interval, possibly due to receptor desensitization. 5. The Mg- and curare-sensitive conductance is also blocked by 1 mM-ACh. 6. The data are consistent with the hypothesis that the hyperpolarization following action potentials in each of these four neurones is produced by a self-inhibitory synaptic mechanism.

This article has been cited by other articles:

				C. G. Evans, A. Romero, and E. C. Cropper Inhibition of Afferent Transmission in the Feeding Circuitry of Aplysia: Persistence Can Be as Important as Size J Neurophysiol, May 1, 2005; 93(5): 2940 - 2949. [Abstract] [Full Text] [PDF]

				T. P. Norekian GABAergic Excitatory Synapses and Electrical Coupling Sustain Prolonged Discharges in the Prey Capture Neural Network of Clione limacina J. Neurosci., March 1, 1999; 19(5): 1863 - 1875. [Abstract] [Full Text] [PDF]