| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1. Substrate utilization in the legs during bicycle exercise was studied in five subjects when performing intermittent intense exercise (15 sec work--15 sec rest) as well as continuous exercise during 60 min, with an almost identical average power output and oxygen uptake in both situations. 2. Muscle biopsies were obtained from vastus lateralis at rest, during, and after exercise in order to determine intramuscular lipid and carbohydrate utilization. The contribution from blood-borne substrates to total oxidative metabolism was determined by arterial-femoral venous (a-fv) differences for oxygen, FFA, glucose, and lactate and leg blood flow. 3. Intermittent and continuous exercise revealed a similar glycogen depletion and the intramuscular lactate accumulation was rather small. A similar uptake of blood-borne substrate (FFA, glucose) was found in both situations whereas a release of lactate only was observed in intermittent exercise. 4. ATP and CP levels oscillated between work and rest periods in intermittent exercise but were not resynthesized to resting levels at the end of the rest periods. The mainly aerobic energy release during each work period in intermittent exercise is partly caused by myoglobin functioning as an oxygen store; this factor was calculated to be more important than ATP and CP or lactate level oscillations. 5. The metabolic response to intermittent exercise was found to be similar to that found in continuous exercise with approximately the same average power output and oxygen uptake. This indicates that some factor in the intermediary metabolism, for instance citrate, functions as a regulator retarding glycolysis and favouring lipid utilization and an aerobic energy release in intermittent exercise.
This article has been cited by other articles:
|
|
 |
|
  E. G. Trapp, D. J. Chisholm, and S. H. Boutcher Metabolic response of trained and untrained women during high-intensity intermittent cycle exercise Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2007; 293(6): R2370 - R2375. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Kiens Skeletal Muscle Lipid Metabolism in Exercise and Insulin Resistance Physiol Rev, January 1, 2006; 86(1): 205 - 243. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Roepstorff, B. Vistisen, M. Donsmark, J. N Nielsen, H. Galbo, K. A Green, D. G. Hardie, J. F. P Wojtaszewski, E. A Richter, and B. Kiens Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise J. Physiol., October 15, 2004; 560(2): 551 - 562. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. J. C. van Loon Use of intramuscular triacylglycerol as a substrate source during exercise in humans J Appl Physiol, October 1, 2004; 97(4): 1170 - 1187. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Mittendorfer, D. A. Fields, and S. Klein Excess body fat in men decreases plasma fatty acid availability and oxidation during endurance exercise Am J Physiol Endocrinol Metab, March 1, 2004; 286(3): E354 - E362. [Abstract] [Full Text]
|
|
|
|
|
|
L. J. C. van Loon, V. B. Schrauwen-Hinderling, R. Koopman, A. J. M. Wagenmakers, M. K. C. Hesselink, G. Schaart, M. E. Kooi, and W. H. M. Saris Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in trained males Am J Physiol Endocrinol Metab, October 1, 2003; 285(4): E804 - E811. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Watt, G. J. F. Heigenhauser, and L. L. Spriet Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: is there a controversy? J Appl Physiol, October 1, 2002; 93(4): 1185 - 1195. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Howald, C. Boesch, R. Kreis, S. Matter, R. Billeter, B. Essen-Gustavsson, and H. Hoppeler Content of intramyocellular lipids derived by electron microscopy, biochemical assays, and 1H-MR spectroscopy J Appl Physiol, June 1, 2002; 92(6): 2264 - 2272. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Larson-Meyer, B. R. Newcomer, and G. R. Hunter Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study Am J Physiol Endocrinol Metab, January 1, 2002; 282(1): E95 - E106. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Krssak, K. F. Petersen, R. Bergeron, T. Price, D. Laurent, D. L. Rothman, M. Roden, and G. I. Shulman Intramuscular Glycogen and Intramyocellular Lipid Utilization during Prolonged Exercise and Recovery in Man: A 13C and 1H Nuclear Magnetic Resonance Spectroscopy Study J. Clin. Endocrinol. Metab., February 1, 2000; 85(2): 748 - 754. [Abstract] [Full Text]
|
|
|
|
 |
|
 P. T. Williams Relationships of Heart Disease Risk Factors to Exercise Quantity and Intensity Arch Intern Med, February 9, 1998; 158(3): 237 - 245. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. D. Starling, T. A. Trappe, A. C. Parcell, C. G. Kerr, W. J. Fink, and D. L. Costill Effects of diet on muscle triglyceride and endurance performance J Appl Physiol, April 1, 1997; 82(4): 1185 - 1189. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
