| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Two Rhesus monkeys (Macaca mulatta) were trained to pursue a target light signal by moving the hand at the wrist joint. Additionally, a d.c. motor could be attached to the lever in order to perform similar passive movements. During performance of the task, single Purkinje cells were recorded from the intermediate part of the cerebellar anterior lobe. Electromyographic activity of the flexor and extensor muscles of the forearm was recorded simultaneously. Passive hand movements evoked changes in the complex spike and simple spike discharge of Purkinje cell. The complex spike responded most sensitively to the beginning of the movement; the activity pattern had phasic character and could be related specifically to the movement direction. The simple spike response was usually weak and hence revealed-less specific relations. During active movements the simple spike frequency change was generally stronger than during passive movements and reached a maximum (or minimum) at the beginning of hand deflexion. The complex spike activity during active movements was characterized by a contrast between the time phases before and after the movement onset. In most of the cases, where a phase of increased activity stopped at the movement onset, the sensory feed-back signal seen during passive movements was cancelled. The possible consequences of the convergence of the complex and simple spike signal for the motor control function of the cerebellum are discussed.
This article has been cited by other articles:
|
|
 |
|
  N. Hagura, Y. Oouchida, Y. Aramaki, T. Okada, M. Matsumura, N. Sadato, and E. Naito Visuokinesthetic Perception of Hand Movement Is Mediated by Cerebro-Cerebellar Interaction between the Left Cerebellum and Right Parietal Cortex Cereb Cortex, May 2, 2008; (2008) bhn068v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. R. Mason, C. M. Hendrix, and T. J. Ebner Purkinje Cells Signal Hand Shape and Grasp Force During Reach-to-Grasp in the Monkey J Neurophysiol, January 1, 2006; 95(1): 144 - 158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Pardoe, S. A. Edgley, T. Drew, and R. Apps Changes in Excitability of Ascending and Descending Inputs to Cerebellar Climbing Fibers during Locomotion J. Neurosci., March 17, 2004; 24(11): 2656 - 2666. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. J. EBNER, M. T. V. JOHNSON, A. ROITMAN, and Q. FU What Do Complex Spikes Signal about Limb Movements? Ann. N.Y. Acad. Sci., December 1, 2002; 978(1): 205 - 218. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. R. GIBSON, K. M. HORN, and M. PONG Inhibitory Control of Olivary Discharge Ann. N.Y. Acad. Sci., December 1, 2002; 978(1): 219 - 231. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Naito, T. Kochiyama, R. Kitada, S. Nakamura, M. Matsumura, Y. Yonekura, and N. Sadato Internally Simulated Movement Sensations during Motor Imagery Activate Cortical Motor Areas and the Cerebellum J. Neurosci., May 1, 2002; 22(9): 3683 - 3691. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q.-G. Fu, D. Flament, J. D. Coltz, and T. J. Ebner Relationship of Cerebellar Purkinje Cell Simple Spike Discharge to Movement Kinematics in the Monkey J Neurophysiol, July 1, 1997; 78(1): 478 - 491. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L M Parsons, J M Bower, J H Gao, J Xiong, J Li, and P T Fox Lateral cerebellar hemispheres actively support sensory acquisition and discrimination rather than motor control. Learn. Mem., January 1, 1997; 4(1): 49 - 62. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
