| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Psychology Department, Dalhousie University, Halifax, N.S., Canada.
1. The rate and extent of recovery of vision was studied in the deprived eye of kittens that had been monocularly deprived from near birth for periods that lasted from 6 weeks to 18 months. Recovery was measured in the two situations, where either both eyes were open following the initial deprivation (binocular recovery), or else the non-deprived eye was occluded so as to force the animal to employ its deprived eye (reverse occlusion). 2. Measurements were made of the visual acuity of the deprived eye for gratings at frequent intervals during recovery by means of a simple behavioural technique. 3. The acuity that the deprived eye eventually attained declined with increasing length of deprivation in a manner that could be approximated by a simple exponential decay. Only minimal visual recovery was observed in animals deprived beyond 1 year of age; only two of six animals recovered sufficient vision to enable measurement of visual acuity. In general, animals that were reverse occluded recovered better vision than did those that had both eyes open during recovery. 4. The recovery of vision in the deprived eye of monocularly deprived kittens was compared to that observed following equivalent periods of two forms of binocular deprivation, namely dark-rearing and binocular eyelid suture. 5. The recovery from the two forms of binocular deprivation was quite different. Whereas the extent of recovery from dark-rearing was considerably greater than that observed after equivalent periods of monocular deprivation, the recovery of a limited sample of cats that were binocularly deprived by eyelid suture was worse. 6. These findings suggest that some plasticity remains in the visual pathways for a longer time than indicated by experiments that examine the physiological effects of monocular deprivation on various visual cortical structures.
This article has been cited by other articles:
|
|
 |
|
  Q. S. Fischer, S. Aleem, H. Zhou, and T. A. Pham Adult visual experience promotes recovery of primary visual cortex from long-term monocular deprivation Learn. Mem., August 29, 2007; 14(9): 573 - 580. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Iny, A. J. Heynen, E. Sklar, and M. F. Bear Bidirectional modifications of visual acuity induced by monocular deprivation in juvenile and adult rats. J. Neurosci., July 12, 2006; 26(28): 7368 - 7374. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Pizzorusso, P. Medini, S. Landi, S. Baldini, N. Berardi, and L. Maffei Structural and functional recovery from early monocular deprivation in adult rats PNAS, May 30, 2006; 103(22): 8517 - 8522. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. D. Faulkner, V. Vorobyov, and F. Sengpiel Visual Cortical Recovery From Reverse Occlusion Depends on Concordant Binocular Experience J Neurophysiol, March 1, 2006; 95(3): 1718 - 1726. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. D. Faulkner, V. Vorobyov, and F. Sengpiel Limited Protection of the Primary Visual Cortex from the Effects of Monocular Deprivation by Strabismus Cereb Cortex, November 1, 2005; 15(11): 1822 - 1833. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Pham, S. J. Graham, S. Suzuki, A. Barco, E. R. Kandel, B. Gordon, and M. E. Lickey A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB Learn. Mem., November 1, 2004; 11(6): 738 - 747. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Mitchell, G. Gingras, and P. C. Kind Initial recovery of vision after early monocular deprivation in kittens is faster when both eyes are open PNAS, September 25, 2001; 98(20): 11662 - 11667. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
