HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hayes, K Articles by Weaver, L C Search for Related Content PubMed PubMed Citation Articles by Hayes, K Articles by Weaver, L C

John P. Robarts Research Institute, London, Ontario, Canada.

1. Electrical activity of multifibre renal, splenic, mesenteric and greater splanchnic nerves and 13th thoracic white rami was recorded in artificially respired, urethane-anaesthetized rats. Discharge of neurones in the rostral ventrolateral medulla was blocked by unilateral microinjections of the inhibitory amino acid glycine and effects on the electrical activity of these sympathetic nerves were compared. 2. Blockade of the rostral ventrolateral medulla caused greater decreases in discharge of renal than splenic nerves and had no consistent effect on mesenteric nerves. This blockade also decreased the discharge of the preganglionic white rami more than that of the preganglionic splanchnic nerves. 3. Postganglionic responses to rostral ventrolateral medulla blockade were always greater than preganglionic responses. 4. The arterial pressure and renal nerve responses to rostral ventrolateral medulla blockade in urethane-anaesthetized rats were not different from those in rats anaesthetized with alpha-chloralose. 5. These findings demonstrate that pre- and postganglionic sympathetic pathways to the kidney are more dependent upon excitatory drive from the rostral ventrolateral medulla than pathways directed to the spleen and intestine.

This article has been cited by other articles:

				B. Pan, M. R. Zahner, E. Kulikowicz, and L. P. Schramm Effects of corticospinal tract stimulation on renal sympathetic nerve activity in rats with intact and chronically lesioned spinal cords Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2007; 293(1): R178 - R184. [Abstract] [Full Text] [PDF]

				S. Koba, T. Yoshida, and N. Hayashi Differential sympathetic outflow and vasoconstriction responses at kidney and skeletal muscles during fictive locomotion Am J Physiol Heart Circ Physiol, February 1, 2006; 290(2): H861 - H868. [Abstract] [Full Text] [PDF]