HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Garwicz, M. Articles by Ekerot, C.-F. Search for Related Content PubMed PubMed Citation Articles by Garwicz, M. Articles by Ekerot, C.-F.

Cutaneous receptive fields and topography of mossy fibres and climbing fibres projecting to cat cerebellar C3 zone

Martin Garwicz, Henrik Jörntell and Carl-Fredrik Ekerot

1. The topographical organization of mossy fibre input to the forelimb area of the paravermal C3 zone in cerebellar lobules IV and V was investigated in barbiturate-anaesthetized cats and compared with the previously described microzonal organization of climbing fibre input to the same part of the cortex. Recordings were made in the Purkinje cell and granule cell layers from single climbing fibre and mossy fibre units, respectively, and the organization of cutaneous receptive fields was assessed for both types of afferents.

2. Based on spatial characteristics, receptive fields of single mossy fibres could be systematized into ten classes and a total of thirty-two subclasses, mainly in accordance with a scheme previously used for classification of climbing fibres. Different mossy fibres displayed a substantial range of sensitivity to natural peripheral stimulation, responded preferentially to phasic or tonic stimuli and were activated by brushing of hairs or light tapping of the skin.

3. Overall, mossy fibres to any given microzone had receptive fields resembling the climbing fibre receptive field defining that microzone. However, compared with the climbing fibre input, the mossy fibre input had a more intricate topographical organization. Mossy fibres with very similar receptive fields projected to circumscribed cortical regions, with a specific termination not only in the mediolateral, but also in some cases in the rostrocaudal and dorsoventral, dimensions of the zone. On the other hand, mossy fibre units with non-identical, albeit usually similar, receptive fields were frequently found in the same microelectrode track.

This article has been cited by other articles:

				A. Pijpers, R. Apps, J. Pardoe, J. Voogd, and T. J. H. Ruigrok Precise Spatial Relationships between Mossy Fibers and Climbing Fibers in Rat Cerebellar Cortical Zones. J. Neurosci., November 15, 2006; 26(46): 12067 - 12080. [Abstract] [Full Text] [PDF]

				H. Jorntell and C.-F. Ekerot Properties of somatosensory synaptic integration in cerebellar granule cells in vivo. J. Neurosci., November 8, 2006; 26(45): 11786 - 11797. [Abstract] [Full Text] [PDF]

				M. Berends, R. Maex, and E. De Schutter The Effect of NMDA Receptors on Gain Modulation Neural Comput., December 1, 2005; 17(12): 2531 - 2547. [Abstract] [Full Text] [PDF]

				N. C. Rowland and D. Jaeger Coding of Tactile Response Properties in the Rat Deep Cerebellar Nuclei J Neurophysiol, August 1, 2005; 94(2): 1236 - 1251. [Abstract] [Full Text] [PDF]

				F. Odeh, R. Ackerley, J. G. Bjaalie, and R. Apps Pontine Maps Linking Somatosensory and Cerebellar Cortices Are in Register with Climbing Fiber Somatotopy J. Neurosci., June 15, 2005; 25(24): 5680 - 5690. [Abstract] [Full Text] [PDF]

				H. Jorntell and C.-F. Ekerot Receptive Field Plasticity Profoundly Alters the Cutaneous Parallel Fiber Synaptic Input to Cerebellar Interneurons In Vivo J. Neurosci., October 22, 2003; 23(29): 9620 - 9631. [Abstract] [Full Text] [PDF]

				J. Voogd, J. Pardoe, T. J. H. Ruigrok, and R. Apps The Distribution of Climbing and Mossy Fiber Collateral Branches from the Copula Pyramidis and the Paramedian Lobule: Congruence of Climbing Fiber Cortical Zones and the Pattern of Zebrin Banding within the Rat Cerebellum J. Neurosci., June 1, 2003; 23(11): 4645 - 4656. [Abstract] [Full Text] [PDF]

				S. L. Baader, M. W. Vogel, S. Sanlioglu, X. Zhang, and J. Oberdick Selective Disruption of "Late Onset" Sagittal Banding Patterns by Ectopic Expression of Engrailed-2 in Cerebellar Purkinje Cells J. Neurosci., July 1, 1999; 19(13): 5370 - 5379. [Abstract] [Full Text] [PDF]

				M. Garwicz, A. Levinsson, and J. Schouenborg Common principles of sensory encoding in spinal reflex modules and cerebellar climbing fibres J. Physiol., May 1, 2002; 540(3): 1061 - 1069. [Abstract] [Full Text] [PDF]