HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Riddell, J. S. Articles by Hadian, M. Search for Related Content PubMed PubMed Citation Articles by Riddell, J. S. Articles by Hadian, M.

Interneurones in pathways from group II muscle afferents in the lower-lumbar segments of the feline spinal cord

J. S. Riddell and M. Hadian

1. Interneurones receiving excitatory input from group II muscle afferents of hindlimb nerves and located in the lower-lumbar (L6-L7) segments of the cat spinal cord were investigated using both extracellular and intracellular recording.

2. The interneurones were located mainly in the lateral parts of laminae IV-VII, dorsal and lateral to the main region in which interneurones with input from group I muscle afferents are located. Almost half the sample of interneurones (38 of 76) were characterized by an ipsilateral ascending projection within the lateral funiculus to the L4 level.

3. The most powerful group II excitation was produced by afferents of the quadriceps and deep peroneal muscle nerves (which discharged 70-80 % of extracellularly recorded neurones) while group II afferents of tibialis posterior, posterior biceps-semitendinosus and gastrocnemius soleus were also highly effective (discharging 45-55 % of extracellularly recorded neurones). A proportion of intracellularly recorded group II EPSPs were monosynaptic.

4. Seventy-five per cent of the extracellularly recorded interneurones were discharged by group II afferents of two or more muscle nerves and 43 % by afferents of three or more nerves.

5. Group I muscle afferents evoked small EPSPs in over one-quarter of the intracellularly recorded interneurones and virtually all were strongly excited by cutaneous afferents. Evidence of excitatory input from joint, interosseous and group III muscle afferents was also observed.

6. The properties of the interneurones are compared with those of others in the lumbosacral segments and the possibility that they may function as last-order premotor interneurones is discussed.

This article has been cited by other articles:

				H. Delivet-Mongrain, H. Leblond, and S. Rossignol Effects of Localized Intraspinal Injections of a Noradrenergic Blocker on Locomotion of High Decerebrate Cats J Neurophysiol, August 1, 2008; 100(2): 907 - 921. [Abstract] [Full Text] [PDF]

				E. Jankowska and A. Puczynska Interneuronal Activity in Reflex Pathways from Group II Muscle Afferents Is Monitored by Dorsal Spinocerebellar Tract Neurons in the Cat J. Neurosci., April 2, 2008; 28(14): 3615 - 3622. [Abstract] [Full Text] [PDF]

				D. Barthelemy, H. Leblond, and S. Rossignol Characteristics and Mechanisms of Locomotion Induced by Intraspinal Microstimulation and Dorsal Root Stimulation in Spinal Cats J Neurophysiol, March 1, 2007; 97(3): 1986 - 2000. [Abstract] [Full Text] [PDF]

				E. Jankowska, S. A. Edgley, P. Krutki, and I. Hammar Functional differentiation and organization of feline midlumbar commissural interneurones J. Physiol., June 1, 2005; 565(2): 645 - 658. [Abstract] [Full Text] [PDF]

				M. J Angel, E Jankowska, and D. A McCrea Candidate interneurones mediating group I disynaptic EPSPs in extensor motoneurones during fictive locomotion in the cat J. Physiol., March 1, 2005; 563(2): 597 - 610. [Abstract] [Full Text] [PDF]

				S. C. Gandevia Spinal and Supraspinal Factors in Human Muscle Fatigue Physiol Rev, October 1, 2001; 81(4): 1725 - 1789. [Abstract] [Full Text] [PDF]