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Email: joyner.michael{at}mayo.edu
Blood pressure rises with exercise. What governs this response? In this issue of The Journal of Physiology, Vissing and colleagues explore the nature of the substances (metabolites?) produced by contracting muscles that stimulate fine afferents in the active muscles and evoke a reflex increase in arterial pressure. Their provocative observations are the latest in over 100 years of investigation on this topic.
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