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ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina
J Physiol Kawamura et al. 10.1113/jphysiol.2003.047977.

Time-lapse movie showing BzATP-induced contraction of a pericyte-containing microvessel.

When ‘BzATP’ is shown in the lower right corner of this continuously looping movie, the perfusate contained 100 µM of this P2X7 agonist. Note that some of the red blood cells were displaced as the pericytes contracted and the lumen narrowed. Frames were acquired every 8 s for 13.3 min. The scale bar shows 10 µm. BzATP induces pericyte contraction and lumen constriction in retinal microvessels.

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