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First published online on June 29, 2006.
 Copyright © 2006 by The Physiological Society
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jphysiol.2006.112623v1
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Received May 1, 2006
Revised May 28, 2006
Accepted after revision June 21, 2006

Microarrays and the microscope: Balancing throughput with resolution

Giovanni Coppola1 and Daniel H Geschwind1*

1 UCLA

* To whom correspondence should be addressed. E-mail: dhg{at}mednet.ucla.edu.

The cellular complexity of the brain is a major issue in the planning, execution and interpretation of microarray studies. Recent technical advances allow for high-throughput study of specific cell populations and circuits. Here we review representative examples of currently available methods that allow high resolution and specificity in brain microarray studies, while maintaining the goal of comprehensive, high-throughput analysis.


Key words: Gene expression




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