PERSPECTIVES:

Iain A. Greenwood

CLC-3 knockout hints at swelling-activated chloride channel complexity
J Physiol 2004 557: 343. First Published online on March 12, 2004 [Full Text] [PDF]  

T. G. West

Controlling pyruvate oxidation in endurance-trained skeletal muscle
J Physiol 2004 557: 344. First Published online on April 2, 2004 [Full Text] [PDF]  

Hans C. Haverkamp and Jerome A. Dempsey

On the normal variability of gas exchange efficiency during exercise: does sex matter?
J Physiol 2004 557: 345. First Published online on April 2, 2004 [Full Text] [PDF]  

Robert Boushel and Michael Kjær

Redundancy reflects versatility of blood flow regulation mechanisms
J Physiol 2004 557: 346. First Published online on April 23, 2004 [Full Text] [PDF]  

RAPID REPORTS:

Michael Dabrowski, Andrei Tarasov, and Frances M. Ashcroft

Mapping the architecture of the ATP-binding site of the K_ATP channel subunit Kir6.2
J Physiol 2004 557: 347-354. First Published online on March 5, 2004 [Abstract] [Full Text] [PDF]  

Brent Fedirchuk and Yue Dai

Monoamines increase the excitability of spinal neurones in the neonatal rat by hyperpolarizing the threshold for action potential production
J Physiol 2004 557: 355-361. First Published online on April 16, 2004 [Abstract] [Full Text] [PDF]  

RESEARCH PAPERS:

Raúl Estévez, Michael Pusch, Carles Ferrer-Costa, Modesto Orozco, and Thomas J. Jentsch

Functional and structural conservation of CBS domains from CLC chloride channels
J Physiol 2004 557: 363-378. First Published online on January 14, 2004 [Abstract] [Full Text] [PDF]  

Maëlle Jospin, Marie-Christine Mariol, Laurent Segalat, and Bruno Allard

Patch clamp study of the UNC-105 degenerin and its interaction with the LET-2 collagen in Caenorhabditis elegans muscle
J Physiol 2004 557: 379-388. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF] Supplementary Movies  

Martin Mortensen, Uffe Kristiansen, Bjarke Ebert, Bente Frølund, Povl Krogsgaard-Larsen, and Trevor G. Smart

Activation of single heteromeric GABA_A receptor ion channels by full and partial agonists
J Physiol 2004 557: 389-413. First Published online on February 27, 2004 [Abstract] [Full Text] [PDF]  

Galit Fuhrmann, Anna Cowan, Idan Segev, Misha Tsodyks, and Christian Stricker

Multiple mechanisms govern the dynamics of depression at neocortical synapses of young rats
J Physiol 2004 557: 415-438. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

Shintaro Yamamoto-Mizuma, Ge-Xin Wang, Luis L. Liu, Kathleen Schegg, William J. Hatton, Dayue Duan, The Late Burton Horowitz, Fred S. Lamb, and Joseph R. Hume

Altered properties of volume-sensitive osmolyte and anion channels (VSOACs) and membrane protein expression in cardiac and smooth muscle myocytes from Clcn3^-/- mice
J Physiol 2004 557: 439-456. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

M. Teresa Pérez-García, Olaia Colinas, Eduardo Miguel-Velado, Alejandro Moreno-Domínguez, and José Ramón López-López

Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing
J Physiol 2004 557: 457-471. First Published online on March 19, 2004 [Abstract] [Full Text] [PDF]  

Claire Leroy, Pierrick Poisbeau, A. Florence Keller, and Astrid Nehlig

Pharmacological plasticity of GABA_A receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy
J Physiol 2004 557: 473-487. First Published online on March 19, 2004 [Abstract] [Full Text] [PDF]  

Marzia Martina, Yelena Gorfinkel, Samantha Halman, John A. Lowe, Pranav Periyalwar, Christopher J. Schmidt, and Richard Bergeron

Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
J Physiol 2004 557: 489-500. First Published online on April 2, 2004 [Abstract] [Full Text] [PDF]  

Scott Trappe, Todd Trappe, Philip Gallagher, Matthew Harber, Bjorn Alkner, and Per Tesch

Human single muscle fibre function with 84 day bed-rest and resistance exercise
J Physiol 2004 557: 501-513. First Published online on April 2, 2004 [Abstract] [Full Text] [PDF]  

Toshio Kitazawa, Atsuko N. Polzin, and Masumi Eto

CPI-17-deficient smooth muscle of chicken
J Physiol 2004 557: 515-528. First Published online on April 16, 2004 [Abstract] [Full Text] [PDF]  

I. Mark Olfert, Jamal Balouch, Axel Kleinsasser, Amy Knapp, Harrieth Wagner, Peter D. Wagner, and Susan R. Hopkins

Does gender affect human pulmonary gas exchange during exercise?
J Physiol 2004 557: 529-541. First Published online on February 27, 2004 [Abstract] [Full Text] [PDF]  

Brendan J. Canning, Stuart B. Mazzone, Sonya N. Meeker, Nanako Mori, Sandra M. Reynolds, and Bradley J. Undem

Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs
J Physiol 2004 557: 543-558. First Published online on March 5, 2004 [Abstract] [Full Text] [PDF]  

Paul J. LeBlanc, Sandra J. Peters, Rebecca J. Tunstall, David Cameron-Smith, and George J. F. Heigenhauser

Effects of aerobic training on pyruvate dehydrogenase and pyruvate dehydrogenase kinase in human skeletal muscle
J Physiol 2004 557: 559-570. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

L. Jensen, J. Bangsbo, and Y. Hellsten

Effect of high intensity training on capillarization and presence of angiogenic factors in human skeletal muscle
J Physiol 2004 557: 571-582. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

Joachim R. Ehrlich, Tae-Joon Cha, Liming Zhang, Denis Chartier, Louis Villeneuve, Terence E. Hébert, and Stanley Nattel

Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium
J Physiol 2004 557: 583-597. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

William G. Schrage, Michael J. Joyner, and Frank A. Dinenno

Local inhibition of nitric oxide and prostaglandins independently reduces forearm exercise hyperaemia in humans
J Physiol 2004 557: 599-611. First Published online on March 26, 2004 [Abstract] [Full Text] [PDF]  

Walter Marcotti, Stuart L. Johnson, and Corné J. Kros

Effects of intracellular stores and extracellular Ca²⁺ on Ca²⁺-activated K⁺ currents in mature mouse inner hair cells
J Physiol 2004 557: 613-633. First Published online on April 2, 2004 [Abstract] [Full Text] [PDF]  

Colin G. Egan, John C. Lockhart, and William R. Ferrell

Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation
J Physiol 2004 557: 635-643. First Published online on April 2, 2004 [Abstract] [Full Text] [PDF]  

R. W. Bavis, E. B. Olson, Jr, E. H. Vidruk, D. D. Fuller, and G. S. Mitchell

Developmental plasticity of the hypoxic ventilatory response in rats induced by neonatal hypoxia
J Physiol 2004 557: 645-660. First Published online on March 12, 2004 [Abstract] [Full Text] [PDF]  

Margaret J. Sullivan, Eileen M. Hasser, Julia A. Moffitt, Stacy B. Bruno, and J. Thomas Cunningham

Rats exhibit aldosterone-dependent sodium appetite during 24 h hindlimb unloading
J Physiol 2004 557: 661-670. First Published online on March 26, 2004 [Abstract] [Full Text] [PDF]  

Christoph Rummel, Thomas Hübschle, Rüdiger Gerstberger, and Joachim Roth

Nuclear translocation of the transcription factor STAT3 in the guinea pig brain during systemic or localized inflammation
J Physiol 2004 557: 671-687. First Published online on February 13, 2004 [Abstract] [Full Text] [PDF]  

Zafiris J. Daskalakis, Guillermo O. Paradiso, Bruce K. Christensen, Paul B. Fitzgerald, Carolyn Gunraj, and Robert Chen

Exploring the connectivity between the cerebellum and motor cortex in humans
J Physiol 2004 557: 689-700. First Published online on March 26, 2004 [Abstract] [Full Text] [PDF]  

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