Perspectives:

Michael J. Rennie

A role for leucine in rejuvenating the anabolic effects of food in old rats
J Physiol 2005 569: 357. First Published online on October 6, 2005 [Full Text] [PDF]  

Topical Review:

Mack H. Wu

Endothelial focal adhesions and barrier function
J Physiol 2005 569: 359-366. First Published online on September 29, 2005 [Abstract] [Full Text] [PDF]  

MOLECULAR AND GENOMIC PHYSIOLOGY:

   Research Papers:

Rajesh N. Subbiah, Mari Kondo, Terence J. Campbell, and Jamie I. Vandenberg

Tryptophan scanning mutagenesis of the HERG K⁺ channel: the S4 domain is loosely packed and likely to be lipid exposed
J Physiol 2005 569: 367-379. First Published online on September 15, 2005 [Abstract] [Full Text] [PDF] Supplemental Data  

Kevin Erreger and Stephen F. Traynelis

Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors
J Physiol 2005 569: 381-393. First Published online on September 15, 2005 [Abstract] [Full Text] [PDF]  

Stephanie Schorge, Sergio Elenes, and David Colquhoun

Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits
J Physiol 2005 569: 395-418. First Published online on October 13, 2005 [Abstract] [Full Text] [PDF]  

Deri Morgan, Vladimir V. Cherny, Ricardo Murphy, Ben Z. Katz, and Thomas E. DeCoursey

The pH dependence of NADPH oxidase in human eosinophils
J Physiol 2005 569: 419-431. First Published online on September 29, 2005 [Abstract] [Full Text] [PDF]  

Thomas H. Rhodes, Carlos G. Vanoye, Iori Ohmori, Ikuo Ogiwara, Kazuhiro Yamakawa, and Alfred L. George, Jr

Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic–clonic seizures
J Physiol 2005 569: 433-445. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

Zhen Zhou, Xiaohui Wang, Min Li, Yoshiro Sohma, Xiaoqin Zou, and Tzyh-Chang Hwang

High affinity ATP/ADP analogues as new tools for studying CFTR gating
J Physiol 2005 569: 447-457. First Published online on October 13, 2005 [Abstract] [Full Text] [PDF] Supplemental Data  

CELL PHYSIOLOGY:

   Rapid Reports:

Hikaru Hashitani, A. Pilar Garcia-Londoño, G. David S. Hirst, and Frank R. Edwards

Atypical slow waves generated in gastric corpus provide dominant pacemaker activity in guinea pig stomach
J Physiol 2005 569: 459-465. First Published online on October 13, 2005 [Abstract] [Full Text] [PDF]  

David J. Marcinek, Kenneth A. Schenkman, Wayne A. Ciesielski, Donghoon Lee, and Kevin E. Conley

Reduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle
J Physiol 2005 569: 467-473. First Published online on October 27, 2005 [Abstract] [Full Text] [PDF]  

   Research Papers:

Shelby B. Dietz and Venkatesh N. Murthy

Contrasting short-term plasticity at two sides of the mitral–granule reciprocal synapse in the mammalian olfactory bulb
J Physiol 2005 569: 475-488. First Published online on September 15, 2005 [Abstract] [Full Text] [PDF] Supplemental Data  

Lydie Combaret, Dominique Dardevet, Isabelle Rieu, Marie-Noëlle Pouch, Daniel Béchet, Daniel Taillandier, Jean Grizard, and Didier Attaix

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle
J Physiol 2005 569: 489-499. First Published online on September 29, 2005 [Abstract] [Full Text] [PDF]  

Alex Straiker and Ken Mackie

Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones
J Physiol 2005 569: 501-517. First Published online on September 22, 2005 [Abstract] [Full Text] [PDF]  

Wei Yang, Guangdong Yang, Xuming Jia, Lingyun Wu, and Rui Wang

Activation of K_ATP channels by H₂S in rat insulin-secreting cells and the underlying mechanisms
J Physiol 2005 569: 519-531. First Published online on September 22, 2005 [Abstract] [Full Text] [PDF]  

Debbi MacMillan, Susan Chalmers, Thomas C. Muir, and John G. McCarron

IP₃-mediated Ca²⁺ increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP₃-mediated Ca²⁺ increases in guinea-pig colonic smooth muscle cells
J Physiol 2005 569: 533-544. First Published online on September 29, 2005 [Abstract] [Full Text] [PDF]  

Simin Khavandgar, Joy T. Walter, Kristin Sageser, and Kamran Khodakhah

Kv1 channels selectively prevent dendritic hyperexcitability in rat Purkinje cells
J Physiol 2005 569: 545-557. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

INTEGRATIVE PHYSIOLOGY:

   Research Papers:

Hisayoshi Ishii, Takeharu Niioka, Emi Sudo, and Hiroshi Izumi

Evidence for parasympathetic vasodilator fibres in the rat masseter muscle
J Physiol 2005 569: 617-629. First Published online on July 28, 2005 [Abstract] [Full Text] [PDF]  

Helge Wiig, Olav Tenstad, and the late Joel L. Bert

Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro
J Physiol 2005 569: 631-641. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

Revaz O. Solomonia, Adam Kotorashvili, Tamar Kiguradze, Brian J. McCabe, and Gabriel Horn

Ca²⁺/calmodulin protein kinase II and memory: learning-related changes in a localized region of the domestic chick brain
J Physiol 2005 569: 643-653. First Published online on September 22, 2005 [Abstract] [Full Text] [PDF]  

Weiqing Ge, Cynthia R. Long, and Joel G. Pickar

Vertebral position alters paraspinal muscle spindle responsiveness in the feline spine: effect of positioning duration
J Physiol 2005 569: 655-665. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

Claudio Marconi, Mauro Marzorati, Daniele Sciuto, Alessandra Ferri, and Paolo Cerretelli

Economy of locomotion in high-altitude Tibetan migrants exposed to normoxia
J Physiol 2005 569: 667-675. First Published online on September 22, 2005 [Abstract] [Full Text] [PDF]  

Raymond F. Reynolds and Brian L. Day

Visual guidance of the human foot during a step
J Physiol 2005 569: 677-684. First Published online on September 22, 2005 [Abstract] [Full Text] [PDF]  

Satoru Matayoshi, Nan Jiang, Toshihiko Katafuchi, Kohei Koga, Hidemasa Furue, Toshiharu Yasaka, Terumasa Nakatsuka, Xin-Fu Zhou, Yasuhiko Kawasaki, Nobuyuki Tanaka, and Megumu Yoshimura

Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during inflammation in the rat
J Physiol 2005 569: 685-695. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

Shigehiko Ogoh, R. Matthew Brothers, Quinton Barnes, Wendy L. Eubank, Megan N. Hawkins, Sushmita Purkayastha, Albert O-Yurvati, and Peter B. Raven

The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exercise
J Physiol 2005 569: 697-704. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

TISSUE, SYSTEM AND ORGAN PHYSIOLOGY:

   Research Papers:

Stuart B. Mazzone, Nanako Mori, and Brendan J. Canning

Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs
J Physiol 2005 569: 559-573. First Published online on July 28, 2005 [Abstract] [Full Text] [PDF]  

Jian Wei Xu, Mingli Hou, and Malcolm M. Slaughter

Photoreceptor encoding of supersaturating light stimuli in salamander retina
J Physiol 2005 569: 575-585. First Published online on September 1, 2005 [Abstract] [Full Text] [PDF]  

I. Gvilia, C. Angara, D. McGinty, and R. Szymusiak

Different neuronal populations of the rat median preoptic nucleus express c-fos during sleep and in response to hypertonic saline or angiotensin-II
J Physiol 2005 569: 587-599. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

Zsuzsa Bebok, James F. Collawn, John Wakefield, William Parker, Yao Li, Karoly Varga, Eric J. Sorscher, and J. P. Clancy

Failure of cAMP agonists to activate rescued F508 CFTR in CFBE41o^– airway epithelial monolayers
J Physiol 2005 569: 601-615. First Published online on October 6, 2005 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

H. van der Kooij and F. C. T. van der Helm

Observations from unperturbed closed loop systems cannot indicate causality
J Physiol 2005 569: 705. [Full Text] [PDF]  

Ian D. Loram, Martin Lakie, and Constantinos N. Maganaris

Reply from Ian D. Loram, Constantinos N. Maganaris and Martin Lakie
J Physiol 2005 569: 706. [Full Text] [PDF]  

John H. Coote

Found in translation: neural feedback from exercising muscles
J Physiol 2005 569: 707. [Full Text] [PDF]  

Michael J. Joyner

Reply from M. J. Joyner
J Physiol 2005 569: 708. [Full Text] [PDF]  

S Pompéia, GM Manzano, Tufik S, and OFA Bueno

What makes lorazepam different from other benzodiazepines?
J Physiol 2005 569: 709. [Full Text] [PDF]  

Vincenzo Di Lazzaro, Fabio Pilato, Michele Dileone, Pietro A. Tonali, and Ulf Ziemann

Reply from Vincenzo Di Lazzaro, Fabio Pilato, Michele Dileone, Pietro A. Tonali and Ulf Ziemann
J Physiol 2005 569: 710. [Full Text] [PDF]  

Andrew Ramage

Problems of drug selectivity and dose – pharmacology
J Physiol 2005 569: 711. [Full Text] [PDF]  

Martha M. Bosma

Reply from M. M. Bosma
J Physiol 2005 569: 712. [Full Text] [PDF]  

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