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About the Cover

Cover Figure


The cover illustration shows cardiomyocytes from human embryonic stem cells (HESCs) couple with primary human cardiomyocytes during in vitrotransplantation. HESC-derived cardiomyocytes (indicated by red PHKH26 staining) were grown for 24 hours in coculture with primary human fetal cardiomyocytes (tropomyosin stained retrospectively in blue). Lucifer Yellow injected into the HESC-cardiomyocytes (bright green and red coincident) flowed into the primary cardiomycytes through de novo gap junctions (light green cells), indicating functional coupling. Photograph L. Tertoolen, Hubrecht Laboratory. See van Laake et al. pp. 467–478



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