PERSPECTIVES:

Georg Köhr

NMDA receptor antagonists: tools in neuroscience with promise for treating CNS pathologies
J Physiol 2007 581: 1-2. First Published online on March 1, 2007 [Full Text] [PDF]  

J. H. Steinbach

A slip ‘twixt the cup and the lip: a new way to impair function of transmitter-gated channels
J Physiol 2007 581: 3. First Published online on March 22, 2007 [Full Text] [PDF]  

Gonzalo Pizarro

Putting an old dye to a new use
J Physiol 2007 581: 4. First Published online on March 22, 2007 [Full Text] [PDF]  

Dirk Schubert

Observing without disturbing: how different cortical neuron classes represent tactile stimuli
J Physiol 2007 581: 5. First Published online on March 22, 2007 [Full Text] [PDF]  

TOPICAL REVIEW:

Trevor Bushell

The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disorders
J Physiol 2007 581: 7-16. First Published online on March 8, 2007 [Abstract] [Full Text] [PDF]  

MOLECULAR AND GENOMIC:

Moran Rubinstein, Sagit Peleg, Shai Berlin, Dovrat Brass, and Nathan Dascal

G_i3 primes the G protein-activated K⁺ channels for activation by coexpressed G in intact Xenopus oocytes
J Physiol 2007 581: 17-32. First Published online on February 8, 2007 [Abstract] [Full Text] [PDF] Supplemental Data  

Mark D. Parker, Mark T. Young, Christopher M. Daly, Robert W. Meech, Walter F. Boron, and Michael J. A. Tanner

A conductive pathway generated from fragments of the human red cell anion exchanger AE1
J Physiol 2007 581: 33-50. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

Andrew J. R. Plested, Paul J. Groot-Kormelink, David Colquhoun, and Lucia G. Sivilotti

Single-channel study of the spasmodic mutation 1A52S in recombinant rat glycine receptors
J Physiol 2007 581: 51-73. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Peter Gardzinski, David W. K. Lee, Guang-He Fei, Kwokyin Hui, Guan J. Huang, Hong-Shuo Sun, and Zhong-Ping Feng

The role of synaptotagmin I C2A calcium-binding domain in synaptic vesicle clustering during synapse formation
J Physiol 2007 581: 75-90. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

CELLULAR:

Tamara Y. Minosyan, Rong Lu, Mansoureh Eghbali, Ligia Toro, and Enrico Stefani

Increased 5-HT contractile response in late pregnant rat myometrium is associated with a higher density of 5-HT_2A receptors
J Physiol 2007 581: 91-97. First Published online on March 29, 2007 [Abstract] [Full Text] [PDF]  

NEUROSCIENCE:

Michael J. Grey, Jens Bo Nielsen, Nazarena Mazzaro, and Thomas Sinkjær

Positive force feedback in human walking
J Physiol 2007 581: 99-105. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Shashank M. Dravid, Kevin Erreger, Hongjie Yuan, Katherine Nicholson, Phuong Le, Polina Lyuboslavsky, Antoine Almonte, Ernest Murray, Cara Mosley, Jeremy Barber, Adam French, Robert Balster, Thomas F. Murray, and Stephen F. Traynelis

Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block
J Physiol 2007 581: 107-128. First Published online on February 15, 2007 [Abstract] [Full Text] [PDF]  

José María Mateos, Andreas Lüthi, Natasa Savic, Beat Stierli, Peter Streit, Beat H. Gähwiler, and R. Anne McKinney

Synaptic modifications at the CA3–CA1 synapse after chronic AMPA receptor blockade in rat hippocampal slices
J Physiol 2007 581: 129-138. First Published online on February 15, 2007 [Abstract] [Full Text] [PDF]  

C. P. J. de Kock, R. M. Bruno, H. Spors, and B. Sakmann

Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex
J Physiol 2007 581: 139-154. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF] Supplemental data  

Annika Mälkiä, Rodolfo Madrid, Victor Meseguer, Elvira de la Peña, María Valero, Carlos Belmonte, and Félix Viana

Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors
J Physiol 2007 581: 155-174. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF] Supplemental data  

Alexia E. Metz, Nelson Spruston, and Marco Martina

Dendritic D-type potassium currents inhibit the spike afterdepolarization in rat hippocampal CA1 pyramidal neurons
J Physiol 2007 581: 175-187. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF] Supplemental data  

Gita Prabhu, Martin Voss, Thomas Brochier, Luigi Cattaneo, Patrick Haggard, and Roger Lemon

Excitability of human motor cortex inputs prior to grasp
J Physiol 2007 581: 189-201. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Margaret Lin Veruki, Silje Bakken Gill, and Espen Hartveit

Spontaneous IPSCs and glycine receptors with slow kinetics in wide-field amacrine cells in the mature rat retina
J Physiol 2007 581: 203-219. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Chunyan Li, Pradeep K. Tripathi, and William E. Armstrong

Differences in spike train variability in rat vasopressin and oxytocin neurons and their relationship to synaptic activity
J Physiol 2007 581: 221-240. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF] Supplemental data  

Sónia F. A. Santos, Sandra Rebelo, Victor A. Derkach, and Boris V. Safronov

Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of rat
J Physiol 2007 581: 241-254. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Kate S. Stokoe, Richard Balasubramaniam, Catharine A. Goddard, William H. Colledge, Andrew A. Grace, and Christopher L.-H. Huang

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/– murine hearts modelling the Brugada syndrome
J Physiol 2007 581: 255-275. First Published online on February 15, 2007 [Abstract] [Full Text] [PDF]  

Ian N. Sabir, Matthew J. Killeen, Catharine A. Goddard, Glyn Thomas, Simon Gray, Andrew A. Grace, and Christopher L.-H. Huang

Transient alterations in transmural repolarization gradients and arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts
J Physiol 2007 581: 277-289. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

RESPIRATORY:

Andrew Wellman, Atul Malhotra, Amy S. Jordan, Karen Schory, Shiva Gautam, and David P. White

Chemical control stability in the elderly
J Physiol 2007 581: 291-298. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

SKELETAL MUSCLE AND EXERCISE:

Ioannis Vogiatzis, Olga Georgiadou, Maria Koskolou, Dimitrios Athanasopoulos, Konstantinos Kostikas, Spyretta Golemati, Harrieth Wagner, Charis Roussos, Peter D. Wagner, and Spyros Zakynthinos

Effects of hypoxia on diaphragmatic fatigue in highly trained athletes
J Physiol 2007 581: 299-308. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

Deborah Pye, Jesus Palomero, Tabitha Kabayo, and Malcolm J. Jackson

Real-time measurement of nitric oxide in single mature mouse skeletal muscle fibres during contractions
J Physiol 2007 581: 309-318. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Paul C. Pape, Karine Fénelon, Cédric R. H. Lamboley, and Dorothy Stachura

Role of calsequestrin evaluated from changes in free and total calcium concentrations in the sarcoplasmic reticulum of frog cut skeletal muscle fibres
J Physiol 2007 581: 319-367. First Published online on March 1, 2007 [Abstract] [Full Text] [PDF]  

Thomas M. Suchyna and Frederick Sachs

Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes
J Physiol 2007 581: 369-387. First Published online on January 25, 2007 [Abstract] [Full Text] [PDF] Supplemental data  

INTEGRATIVE:

Markus Amann, Lee M. Romer, Andrew W. Subudhi, David F. Pegelow, and Jerome A. Dempsey

Severity of arterial hypoxaemia affects the relative contributions of peripheral muscle fatigue to exercise performance in healthy humans
J Physiol 2007 581: 389-403. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

Shigehiko Ogoh, James P. Fisher, Paul J. Fadel, and Peter B. Raven

Increases in central blood volume modulate carotid baroreflex resetting during dynamic exercise in humans
J Physiol 2007 581: 405-418. First Published online on February 22, 2007 [Abstract] [Full Text] [PDF]  

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