PERSPECTIVES:

Lacy A. Holowatz

Human cutaneous microvascular ageing: potential insights into underlying physiological mechanisms of endothelial function and dysfunction
J Physiol 2008 586: 3301
DOI: 10.1113/jphysiol.2008.157594 [Full Text] [PDF]  

K. A. Gerhold and D. M. Bautista

TRPA1: irritant detector of the airways
J Physiol 2008 586: 3303
DOI: 10.1113/jphysiol.2008.158030 [Full Text] [PDF]  

N. P. Pedersen, P. M. Fuller, J. Lu, and C. B. Saper

In the flicker of an eye
J Physiol 2008 586: 3305-3306
DOI: 10.1113/jphysiol.2008.157768 [Full Text] [PDF]  

TOPICAL REVIEWS:

Geoffrey Burnstock

Unresolved issues and controversies in purinergic signalling
J Physiol 2008 586: 3307-3312 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.155903 [Abstract] [Full Text] [PDF]  

Lena Eliasson, Fernando Abdulkader, Matthias Braun, Juris Galvanovskis, Michael B. Hoppa, and Patrik Rorsman

Novel aspects of the molecular mechanisms controlling insulin secretion
J Physiol 2008 586: 3313-3324 First Published online on May 29, 2008
DOI: 10.1113/jphysiol.2008.155317 [Abstract] [Full Text] [PDF]  

CELLULAR:

Gregory J. Digby, Pooja R. Sethi, and Nevin A. Lambert

Differential dissociation of G protein heterotrimers
J Physiol 2008 586: 3325-3335 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.153965 [Abstract] [Full Text] [PDF]  

NEUROSCIENCE:

J. Hegedus, C. T. Putman, N. Tyreman, and T. Gordon

Preferential motor unit loss in the SOD1^G93A transgenic mouse model of amyotrophic lateral sclerosis
J Physiol 2008 586: 3337-3351 First Published online on May 8, 2008
DOI: 10.1113/jphysiol.2007.149286 [Abstract] [Full Text] [PDF]  

C. P. J. de Kock and B. Sakmann

High frequency action potential bursts ( 100 Hz) in L2/3 and L5B thick tufted neurons in anaesthetized and awake rat primary somatosensory cortex
J Physiol 2008 586: 3353-3364 First Published online on May 15, 2008
DOI: 10.1113/jphysiol.2008.155580 [Abstract] [Full Text] [PDF] Supplemental Data  

Tenpei Akita and Kenji Kuba

Ca²⁺-dependent inactivation of Ca²⁺-induced Ca²⁺ release in bullfrog sympathetic neurons
J Physiol 2008 586: 3365-3384 First Published online on May 15, 2008
DOI: 10.1113/jphysiol.2008.153833 [Abstract] [Full Text] [PDF]  

Enzo Ortu, Franca Deriu, Antonio Suppa, Elena Giaconi, Eusebio Tolu, and John C. Rothwell

Intracortical modulation of cortical-bulbar responses for the masseter muscle
J Physiol 2008 586: 3385-3404 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.153288 [Abstract] [Full Text] [PDF]  

Nanda A. Singh, James F. Otto, E. Jill Dahle, Chris Pappas, Jonathan D. Leslie, Alex Vilaythong, Jeffrey L. Noebels, H. Steve White, Karen S. Wilcox, and Mark F. Leppert

Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization
J Physiol 2008 586: 3405-3423 First Published online on May 15, 2008
DOI: 10.1113/jphysiol.2008.154971 [Abstract] [Full Text] [PDF] Supplemental Data  

Andrew T. E. Hartwick, Claire M. Hamilton, and William H. Baldridge

Glutamatergic calcium dynamics and deregulation of rat retinal ganglion cells
J Physiol 2008 586: 3425-3446 First Published online on May 15, 2008
DOI: 10.1113/jphysiol.2008.154609 [Abstract] [Full Text] [PDF] Supplemental Data  

T. E. Taylor-Clark, M. A. McAlexander, C. Nassenstein, S. A. Sheardown, S. Wilson, J. Thornton, M. J. Carr, and B. J. Undem

Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal
J Physiol 2008 586: 3447-3459 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.153585 [Abstract] [Full Text] [PDF]  

Javier Márquez-Ruiz and Miguel Escudero

Tonic and phasic phenomena underlying eye movements during sleep in the cat
J Physiol 2008 586: 3461-3477 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.153239 [Abstract] [Full Text] [PDF]  

Miguel Escudero and Javier Márquez-Ruiz

Tonic inhibition and ponto-geniculo-occipital-related activities shape abducens motoneuron discharge during REM sleep
J Physiol 2008 586: 3479-3491 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.153254 [Abstract] [Full Text] [PDF]  

Jamie Johnston, Sarah J. Griffin, Claire Baker, Anna Skrzypiec, Tatanya Chernova, and Ian D. Forsythe

Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons
J Physiol 2008 586: 3493-3509 First Published online on May 29, 2008
DOI: 10.1113/jphysiol.2008.153734 [Abstract] [Full Text] [PDF] Supplemental Data  

CARDIOVASCULAR:

Mark A. Black, Daniel J. Green, and N. Timothy Cable

Exercise prevents age-related decline in nitric-oxide-mediated vasodilator function in cutaneous microvessels
J Physiol 2008 586: 3511-3524 First Published online on May 15, 2008
DOI: 10.1113/jphysiol.2008.153742 [Abstract] [Full Text] [PDF]  

Gary P. Van Guilder, Greta L. Hoetzer, Jared J. Greiner, Brian L. Stauffer, and Christopher A. DeSouza

Acute and chronic effects of vitamin C on endothelial fibrinolytic function in overweight and obese adult humans
J Physiol 2008 586: 3525-3535 First Published online on May 22, 2008
DOI: 10.1113/jphysiol.2008.151555 [Abstract] [Full Text] [PDF]  

Han-Zhong Feng, Brandon J. Biesiadecki, Zhi-Bin Yu, M. Moazzem Hossain, and J.-P. Jin

Restricted N-terminal truncation of cardiac troponin T: a novel mechanism for functional adaptation to energetic crisis
J Physiol 2008 586: 3537-3550 First Published online on June 12, 2008
DOI: 10.1113/jphysiol.2008.153577 [Abstract] [Full Text] [PDF]  

SKELETAL MUSCLE AND EXERCISE:

Ole Hartvig Mortensen, Kasper Andersen, Christian Fischer, Anders Rinnov Nielsen, Søren Nielsen, Thorbjörn Åkerström, Maj-brit Aastrøm, Rehannah Borup, and Bente Klarlund Pedersen

Calprotectin is released from human skeletal muscle tissue during exercise
J Physiol 2008 586: 3551-3562 First Published online on May 29, 2008
DOI: 10.1113/jphysiol.2008.153551 [Abstract] [Full Text] [PDF] Supplemental Data  

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