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About the Cover

Cover Figure


The cover illustration shows, top left: drawing of the mouse embryonic spinal cord preparation used in Delpy et al. pp. 1059–1076; top middle: KCC2 staining (green) in a P0 spinal motoneuron (red); top right: KCC2 staining from a E14.5 spinal cord coronal section; middle left: neurobiotin-injected P0 motoneuron; middle centre: NKCC1 staining (blue) in a E13.5 motoneuron (red); middle right: neurobiotin-injected E13.5 motoneuron; bottom left: KCC2 staining from a E16.5 spinal cord coronal section; bottom middle: currents elicited by brief applications of isoguvacine (GABAAR agonist) to E13.5 motoneuron at various holding potentials; bottom right: proposed mechanisms underlying highly depolarizing chloride-mediated responses at E13.5; see Delpy et al. pp. 1059–1076.



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