PERSPECTIVES:

Carlo Reggiani

Between channels and tears: aim at ROS to save the membrane of dystrophic fibres
J Physiol 2008 586: 1779
DOI: 10.1113/jphysiol.2008.152629 [Full Text] [PDF]  

SYMPOSIUM SECTION REPORTS: KV7 (KCNQ) POTASSIUM CHANNELS THAT ARE MUTATED IN HUMAN DISEASES:

David A. Brown

Kv7 (KCNQ) potassium channels that are mutated in human diseases
J Physiol 2008 586: 1781-1783
DOI: 10.1113/jphysiol.2008.153007 [Full Text] [PDF]  

David Peroz, Nicolas Rodriguez, Frank Choveau, Isabelle Baró, Jean Mérot, and Gildas Loussouarn

Kv7.1 (KCNQ1) properties and channelopathies
J Physiol 2008 586: 1785-1789 First Published online on January 3, 2008
DOI: 10.1113/jphysiol.2007.148254 [Abstract] [Full Text] [PDF]  

Snezana Maljevic, Thomas V. Wuttke, and Holger Lerche

Nervous system K_V7 disorders: breakdown of a subthreshold brake
J Physiol 2008 586: 1791-1801 First Published online on January 31, 2008
DOI: 10.1113/jphysiol.2008.150656 [Abstract] [Full Text] [PDF]  

Yoni Haitin and Bernard Attali

The C-terminus of Kv7 channels: a multifunctional module
J Physiol 2008 586: 1803-1810 First Published online on January 24, 2008
DOI: 10.1113/jphysiol.2007.149187 [Abstract] [Full Text] [PDF]  

Ciria C. Hernandez, Oleg Zaika, Gleb P. Tolstykh, and Mark S. Shapiro

Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications
J Physiol 2008 586: 1811-1821 First Published online on January 31, 2008
DOI: 10.1113/jphysiol.2007.148304 [Abstract] [Full Text] [PDF]  

Henrik H. Hansen, Olivier Waroux, Vincent Seutin, Thomas J. Jentsch, Susana Aznar, and Jens D. Mikkelsen

Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS
J Physiol 2008 586: 1823-1832 First Published online on January 3, 2008
DOI: 10.1113/jphysiol.2007.149450 [Abstract] [Full Text] [PDF]  

MOLECULAR AND GENOMIC:

Lai-Hua Xie, Scott A. John, Bernard Ribalet, and James N. Weiss

Phosphatidylinositol-4,5-bisphosphate (PIP₂) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity
J Physiol 2008 586: 1833-1848 First Published online on February 14, 2008
DOI: 10.1113/jphysiol.2007.147868 [Abstract] [Full Text] [PDF]  

NEUROSCIENCE:

Christoph Schmidt-Hieber, Peter Jonas, and Josef Bischofberger

Action potential initiation and propagation in hippocampal mossy fibre axons
J Physiol 2008 586: 1849-1857 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.150151 [Abstract] [Full Text] [PDF] Supplemental Data  

Clarke R. Raymond

Different requirements for action potentials in the induction of different forms of long-term potentiation
J Physiol 2008 586: 1859-1865 First Published online on February 14, 2008
DOI: 10.1113/jphysiol.2008.151035 [Abstract] [Full Text] [PDF]  

Philip de Guzman, Yuji Inaba, Enrica Baldelli, Marco de Curtis, Giuseppe Biagini, and Massimo Avoli

Network hyperexcitability within the deep layers of the pilocarpine-treated rat entorhinal cortex
J Physiol 2008 586: 1867-1883 First Published online on January 31, 2008
DOI: 10.1113/jphysiol.2007.146159 [Abstract] [Full Text] [PDF]  

Ismail Abidin, Ulf T. Eysel, Volkmar Lessmann, and Thomas Mittmann

Impaired GABAergic inhibition in the visual cortex of brain-derived neurotrophic factor heterozygous knockout mice
J Physiol 2008 586: 1885-1901 First Published online on January 31, 2008
DOI: 10.1113/jphysiol.2007.148627 [Abstract] [Full Text] [PDF]  

Grégory Barrière, Maylis Tartas, Jean-René Cazalets, and Sandrine S. Bertrand

Interplay between neuromodulator-induced switching of short-term plasticity at sensorimotor synapses in the neonatal rat spinal cord
J Physiol 2008 586: 1903-1920 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2008.150706 [Abstract] [Full Text] [PDF]  

John A. Hayes, Jeffrey L. Mendenhall, Benjamin R. Brush, and Christopher A. Del Negro

4-Aminopyridine-sensitive outward currents in preBötzinger complex neurons influence respiratory rhythm generation in neonatal mice
J Physiol 2008 586: 1921-1936 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2008.150946 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Carola Förster, Malgorzata Burek, Ignacio A. Romero, Babette Weksler, Pierre-Olivier Couraud, and Detlev Drenckhahn

Differential effects of hydrocortisone and TNF on tight junction proteins in an in vitro model of the human blood–brain barrier
J Physiol 2008 586: 1937-1949 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.146852 [Abstract] [Full Text] [PDF]  

Shigeki Shibata, Jeff L. Hastings, Anand Prasad, Qi Fu, Kazunobu Okazaki, M. Dean Palmer, Rong Zhang, and Benjamin D. Levine

‘Dynamic’ Starling mechanism: effects of ageing and physical fitness on ventricular–arterial coupling
J Physiol 2008 586: 1951-1962 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.143651 [Abstract] [Full Text] [PDF]  

ALIMENTARY:

J. Chevalier, P. Derkinderen, P. Gomes, R. Thinard, P. Naveilhan, P. Vanden Berghe, and M. Neunlist

Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system
J Physiol 2008 586: 1963-1975 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.149815 [Abstract] [Full Text] [PDF]  

RESPIRATORY:

Yunxiang Zhu, Camille Ehre, Lubna H. Abdullah, John K. Sheehan, Michelle Roy, Christopher M. Evans, Burton F. Dickey, and C. William Davis

Munc13-2^–/– baseline secretion defect reveals source of oligomeric mucins in mouse airways
J Physiol 2008 586: 1977-1992 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.149310 [Abstract] [Full Text] [PDF]  

SKELETAL MUSCLE AND EXERCISE:

Sharon A. Jubrias, Nina K. Vollestad, Rod K. Gronka, and Martin J. Kushmerick

Contraction coupling efficiency of human first dorsal interosseous muscle
J Physiol 2008 586: 1993-2002 First Published online on January 31, 2008
DOI: 10.1113/jphysiol.2007.146829 [Abstract] [Full Text] [PDF] Supplemental Data  

Nicholas P. Whitehead, Catherine Pham, Othon L. Gervasio, and David G. Allen

N-Acetylcysteine ameliorates skeletal muscle pathophysiology in mdx mice
J Physiol 2008 586: 2003-2014 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.148338 [Abstract] [Full Text] [PDF]  

INTEGRATIVE:

H. Bond, M. R. Dilworth, B. Baker, E. Cowley, A Requena Jimenez, R. D. H. Boyd, S. M. Husain, B. S. Ward, C. P. Sibley, and J. D. Glazier

Increased maternofetal calcium flux in parathyroid hormone-related protein-null mice
J Physiol 2008 586: 2015-2025 First Published online on February 7, 2008
DOI: 10.1113/jphysiol.2007.149104 [Abstract] [Full Text] [PDF]  

LETTERS:

Samuele Marcora

Is peripheral locomotor muscle fatigue during endurance exercise a variable carefully regulated by a negative feedback system?
J Physiol 2008 586: 2027-2028 First Published online on February 14, 2008
DOI: 10.1113/jphysiol.2008.152470 [Full Text] [PDF]  

Markus Amann and Jerome A. Dempsey

Reply from Markus Amann and Jerome A. Dempsey
J Physiol 2008 586: 2029-2030 First Published online on February 14, 2008
DOI: 10.1113/jphysiol.2008.152496 [Full Text] [PDF]  

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