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Cover Figure


The cover image shows Ca2+ transients in proximal apical dendrites offast-spiking, parvalbumin-expressing hippocampal interneurons. From Aponte et al., pp.2061 . Upper left panel: confocal stack projection ofa dentate gyrus basket cell filled with biocytin and stained with fluorescently labelled avidin. Upper right panel: immunohistochemistry with an antibody against parvalbumin, indicating that the recorded cell is parvalbumin-positive. Lower left panel: infrared differential interference contrast videomicroscopy image ofa dentate gyrus basket cell. Inset shows the fast-spiking action potential phenotype. Lower right panel: fluorescence image ofa basket cell filled with the Ca2+ indicator fura-2, shown together with an overview ofthe morphology (large image). Upper inset indicates Ca2+ transient in the proximal apical dendrite evoked by a train of10 APs. Rectangle in lower inset indicates the region ofinterest used for the Ca2+ measurements.



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